Van de Ven Brace Ends Everton's Run at Brand New Home Ground
The Dutch defender emerged as the initial backline player to score two goals in a Premier League match for Spurs since the Belgian defender in spring 2013.
At a glance
The Spurs defender heads into the net two times in first half
Everton's Jake O'Brien has equalizer disallowed after video check
Pape Matar Sarr nets final goal in dying moments
The defeat is Everton's initial at their new ground
The Tottenham defender found the net on two occasions as Tottenham extended their winning streak on the road in the Premier League and handed Everton their first defeat at their new home.
The Toffees were undefeated in their last five matches at their recently opened stadium at the dockside location, having departed their historic home behind after more than a century at the end of the previous campaign.
But Tottenham's leader the Dutchman struck on two occasions from corners in the opening 45 minutes to place their impressive record at risk, and they were unable to mount a comeback before the midfielder - assisted by ex-Everton forward Richarlison - headed home a final goal to seal the victory.
Jake O'Brien thought he had levelled the scores five minutes after the defender's opener, glancing a bullet header past the Spurs keeper from an Everton corner.
Beto, meanwhile, failed to convert a handful of chances, while the Italian goalkeeper made a series of excellent saves to ensure Tottenham went five matches on the road without defeat in the Premier League.
But the video assistant referee intervened, advising Craig Pawson to review the score on the screen and the referee ruled that Jack Grealish and the attacker were in offside positions and had impeded with the Spurs keeper.
This victory elevates the manager's side into third place in the division, a handful of points off local foes and table-toppers Arsenal.
The Merseyside club stay 14th and sit six points clear of the drop zone.
Spurs breakdown: Van de Ven fulfils duties at both ends of the field
After a drab weekday performance in the European competition against Monaco, where they mustered a only two shots on target, the manager chose the French striker in attack instead of ex-Everton forward Richarlison.
The summer signing was failed to make much of an impact before being substituted for the substitute after 60 minutes on the field, but it turns out he wasn't needed in the end.
Centre-back the Dutchman converted into an offensive threat to be feared.
Tottenham's first goal came from a cleverly executed corner routine, with Rodrigo Bentancur directing the ball back across the six-yard box for an unmarked Van de Ven to head home.
And Ven de Ven - stepping up as captain in the Argentine's absence - added his second in first-half stoppage time as he rose above Jordan Pickford to head home.
The Dutchman was equally outstanding in defence, partnering well with Kevin Danso as the duo dealt superbly with the 34 crosses sent their way by the opposition.
Toffees breakdown: Everton missing finishing touch
Everton's new home had been a happy hunting ground, but it appears the freshness may have faded somewhat and supporters flocked to the exits after the midfielder's final goal for Tottenham.
The break in the team's winning streak at home won't be a major concern for the manager, but their attacking woes are.
The forward and the other striker - the Everton's pair of recognised strikers - had scored just one league goal combined before the weekend's match.
And they were unable to add to that miserable tally on a damp and dreary evening on Merseyside.
Beto's performance was summed up when he chose to overhead kick a clear chance from near the goal, despite having space and opportunity to reposition for a simpler attempt that would have tested the keeper.
Barry, too, failed to make an impact after coming on for the starter in the 65th minute.
It wasn't for a lack of chance. Most of Everton's attacks came through the winger and Ndiaye, who relentlessly whipped threatening crosses into the Tottenham penalty area.
What next for these two sides?
Everton: Moyes' men travel to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Tottenham: Spurs travel to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup tie against the Magpies.